About PreOncology™

Oncologist-led cancer prevention and early detection.

Our Origin Story

Conventional cancer screening was designed to detect the most common cancers in the general population. It was not designed for the individual, and it covers only a fraction of the more than 200 cancers that exist. Many cancers are still diagnosed at an advanced stage each year, when cure is often no longer possible.

PreOncology was founded by oncologists who spent decades on the wrong side of that timeline.

We treated patients after their cancer was found, often too late, often after it had spread, often after the window for early intervention had closed. We saw what worked: early-stage cancers are curable. Late-stage cancers usually are not.

The technology to detect cancer earlier now exists. But no one was integrating it. Patients received fragmented testing with no coordination. Results came back with no guidance on next steps. Primary care physicians were left to navigate a rapidly evolving landscape without the clinical infrastructure to do it rigorously.

We built what the field was missing: a personalized program that brings these technologies together, interprets them through an oncology lens, and delivers the oversight that cancer prevention requires.

Built From First Principles

PreOncology is built from first principles. We are rethinking cancer prevention and early detection at its foundation by defining a new oncology subspecialty, building dynamic risk models that evolve over time, developing surveillance protocols grounded in detection mathematics rather than fixed screening conventions, standardizing upstream signal review, and delivering it all through a medical-grade clinical program integrated with primary care. The result is a new standard of care and a new category in healthcare.

Our Vision

A world where advanced cancer is no longer an expected outcome. Where every person has access to a personalized prevention and early detection program built on oncology expertise and validated, medical-grade science.

Our Mission

To give every member the earliest actionable advantage against cancer, through a program built on oncology expertise, continuous learning, and the conviction that prevention is more powerful than treatment.

Our Leadership Team

Jose Barreau, MD

Founder & Chief Executive Officer

Board-certified medical oncologist and former Medical Director of the TriHealth Cancer Institute. Led clinical operations and cancer care strategy for one of the region’s largest oncology programs. Founded Doc Halo and Halo Health, building healthcare communication platforms used by over 300,000 physicians nationwide. Built PreOncology to move cancer care upstream—from treatment to prevention.

Amit Gupta, MD

Co-Founder & Chief Scientific Officer

Medical Director of The Cancer Center at Springfield Clinic and former Chairman of the Department of Hematology and Oncology.

Co-founder of Halo Health (acquired). Leads PreOncology’s clinical and scientific strategy.

 

Steve Smerz

Chief Technology Officer

Seasoned technology executive with deep expertise in healthcare systems and data infrastructure. Leads PreOncology’s platform architecture, engineering, and technical operations.

Bryan Beaver

VP, Product and Clinical Operations

Healthcare operations leader focused on translating technology into clinical practice. Oversees physician onboarding, practice integration, and operational workflows that bring the PreOncology Platform into real-world care settings.

Jenny Greenland-Zee

Vice President of Marketing

Strategic marketing leader with expertise in healthcare commercialization and growth. Leads PreOncology’s go-to-market strategy, brand positioning, and marketing function. Drives awareness and adoption of the PreOncology Platform across physician and member audiences.

Luke Stetson, Ph.D

Director, Cancer Risk Modeling

Computational scientist specializing in machine learning and cancer biology. Leads development of the Dynamic Risk Engine and Stage Alpha prediction models. Brings rigorous statistical methodology to early cancer detection.

Claire Thomas, Ph.D, MPH

Senior Cancer Epidemiologist

Cancer epidemiologist integrating diverse data sources to advance understanding of cancer etiology and prevention. Former postdoctoral fellow at Fred Hutchinson Cancer Center and AACR NextGen Star, with expertise in epidemiologic study design, causal inference, statistical modeling, and genetic and molecular epidemiology.

Robert Solberg

Director of Product Design

Design leader with nearly 20 years of digital product innovation experience across entrepreneurship and corporate healthcare. Leads PreOncology’s product design with a focus on scalable, user-centered experiences that serve patients and clinicians alike.

Joe Fago

Principal Engineer/Architect

Technology leader with over 20 years of experience designing and scaling enterprise systems across healthcare, finance, and technology. Former CTO at AMV Holdings and Solution Architect at Dark Wolf Solutions and Mutual of Omaha. Brings deep expertise in enterprise architecture, cloud infrastructure, and DevSecOps to PreOncology’s technical operations.

Peter Eisch

Senior DevOps Engineer

Senior technology leader with deep expertise in AWS and a strong track record in startup environments. Has built and led teams at Harmonic Systems, Cable & Wireless, ABILITY Networks, and RedBrick Health. Brings decades of experience in healthcare data infrastructure and enterprise delivery to PreOncology’s engineering operations.

Our Customer Advisory Board

Rich Bova

Customer Advisory Board Member

Former CEO of School Outfitters, with more than two decades of experience scaling organizations and driving revenue transformation. Previously served as Chief Revenue Officer, leading market share growth and strategic planning. Board member at Jewel Craft and TechSolve, with advisory roles across multiple growth-stage companies.

Angel Mena, MD

Customer Advisory Board Member

Internal medicine physician and Program Director at TriHealth, overseeing resident training, evaluation, and clinical supervision.

Chief Medical Officer at symplr, providing strategic clinical direction across healthcare operations, including clinical communication, physician scheduling, and quality and safety solutions.

Terry Bauer

Customer Advisory Board Member

CEO Emeritus of Specialdocs Consultants and board member of its parent company, Kerix Health, a Shore Capital portfolio company. Also serves on the board of directors of Third Federal Savings and Loan (NASDAQ: TFSL) and as an advisor to the Alzheimer’s Treatment Centers of America.

Betsy Neyer

Customer Advisory Board Member

Former President and COO of School Outfitters, where she helped grow the company from a $9M startup to a $170M industry leader. More than two decades of experience in enterprise transformation, operational leadership, and building high-performance organizations. Now advises boards and executive teams on strategy, culture, and scalable growth.

Mike Gross

Customer Advisory Board Member

Nationally recognized intellectual property attorney and founder of the IP Practice at Shook, Hardy & Bacon LLP, which he built into a team of more than 100 professionals. Advised clients including Microsoft, Nike, Oracle, and Pfizer on IP strategy, portfolio development, and transactional risk across more than three decades of practice.

Kelly Wittich

Customer Advisory Board Member

First Vice President–Wealth Management at UBS Financial Services with more than 25 years of industry experience.

CERTIFIED FINANCIAL PLANNER™ (CFP®) specializing in trust and estate planning for P&G families and corporate executives. Active board member and community leader in the Cincinnati area.

 

Our Scientific Advisory Board

Preet Paul Singh, MD

Scientific Advisory Board Member

Board-certified medical oncologist and hematologist trained at the All India Institute of Medical Sciences, University of Alabama, and Mayo Clinic. Practicing oncologist at Springfield Clinic’s Cancer Center, where he brings clinical expertise in gastrointestinal oncology.

Kathleen Curtius, Ph.D

Scientific Advisory Board Member

Assistant Professor of Medicine and Full Member of the Cancer Control Program at UCSD Moores Cancer Center. Leads the Quantitative Cancer Control laboratory, developing mathematical models to improve early cancer detection and prevention through the study of somatic evolution. Ph.D in Applied Mathematics from the University of Washington.

Russell Rockne, Ph.D

Scientific Advisory Board Member

Professor and Director of Mathematical Oncology and Computational Systems Biology at City of Hope, where he has led research for over a decade. Uses mathematical and computational methods to study cancer evolution and response to treatment. Former postdoctoral researcher at Northwestern University’s Feinberg School of Medicine.